Ambajogai, is a city located in Marathwada region of the western Indian state of Maharashtra. Ambajogai is well known for Yogeshwari Temple, which is considered as 1 of 3½ peeths in Maharashtra. It is located 25 kilometres from Parali Vaijnath. Prior Ambajogai was famous in the era for treatment of tuberculosis (TB), and thus the hospital was well known as TB Hospital. The hospital now is renovated and serving various patients and has a Cancer cure wing.There is a memorial of Mukundraj, one of the first poets of Marathi language, nearby in the valley which also gets its name from the poet.The tomb or dargah of Hazrat Sheikh Masood Kirmani is situated near the Swami Ramanand Teerth Rural Medical College which suggests the arrival of Islam in the area around 14th century AD.There is also a proposal given to Maharashtra government for bifurcation of Beed district to form a new Ambajogai District.

The town has been a cultural centre in the region from the ancient times. The Jogai Temple, Kholeshwar Temple and Barakhambi temples hints the cultural prosperity of the town dating back to 10th century AD.The town was under the regime of Nizam of Hyderabad before the accession of Hyderabad state to the dominion of India. It was a military base of the Hyderabad state army. The stable of the horses of the cavalry of the Hyderabad army was later turned into a hospital and medical college which later was named as Swami Ramanand Teerth Rural Medical College.

Ambajogai was once the educational center of Marathwada region and was also called as the Pune of Marathwada. The Swami Ramanand Teerth Education Society was established in the early 20th century making it an educational center even before the independence of India. The legacy is being carried forward by establishing of many schools and colleges, especially by the Government Medical College "Swami Ramanand Teerth Rural Medical College", which is the first rural medical college in Asia[citation needed]. It also has a private Engineering college affiliated to MBES of Latur.

Shri Yogeshwari is a Bhushan of Ambanagari. In the first place, untouchables have embraced literary and culturally respectable Maharashtrian minds. Two of them are remarkable about the poet’s composition Shri Mukundraj and the mausoleum of Navkot Narayan Sant poet Dasopant of Marathi literature. The importance of Ambanagari has increased due to this reason, and in ancient times, this city was sitting in other cities like Bushan ghost (Nagar Bhushan Bhav). Because Yogeshwari had Shaktipeeth, she had attained the form of holy pilgrimage and it is still today.